Implementation Science
Research Portfolio
G-ACT designs and leads implementation science research embedded within real-world health systems to generate rigorous, policy-relevant evidence.
G-ACT designs and leads implementation science research embedded within real-world health systems to generate rigorous, policy-relevant evidence on how proven cardiovascular diagnostics, technologies, and care pathways can be adopted, integrated, and sustained at scale.
All G-ACT studies are independently governed, ethically reviewed, and conducted under IRB approval. Our research portfolio spans validation, implementation, and health systems evaluation moving beyond proof of concept to address the practical conditions required for equitable and sustainable cardiovascular care delivery.
DAMSUN-HF
Detection and Management of Heart Failure with SENSORA in underserved Nations
DAMSUN-HF is a prospective, IRB-approved validation and implementation study evaluating AI-enabled digital auscultation for the detection of heart failure with reduced ejection fraction in frontline clinical settings.
Conducted within routine care environments, the study examines both diagnostic performance and real-world feasibility, including workflow integration, task-shifted use, and referral pathways.
Findings from DAMSUN-HF have been independently reported and published in leading peer-reviewed cardiovascular journals, demonstrating that high-performing diagnostic innovations can be effectively deployed in resource-constrained health systems when implementation is designed for context.
DAMSUN-HF serves as a foundational model for G-ACT's approach to embedding scientific rigor within routine care.
Current Research Portfolio
Building on DAMSUN-HF, G-ACT leads a coordinated portfolio of implementation-focused studies designed to generate complementary evidence across populations, technologies, and health system contexts.
I-HEART
Platform ValidationIntegrated HEART Evaluation and Referral Technology
A platform validation study evaluating the HeartLINK+ system within routine clinical care. The study assesses the feasibility, adoption, and effectiveness of an integrated digital pathway for cardiovascular screening, triage, referral, and specialist decision support.
Focus: How connected technologies can strengthen care coordination and decision-making across levels of the health system.
INSIGHT
Implementation StudyIntelligent Non-Invasive Sonography for Improved Guideline-Aligned Heart Triage
An implementation study examining the use of non-invasive cardiac imaging technologies to support guideline-aligned triage of cardiovascular disease.
Focus: Evaluates diagnostic accuracy alongside workflow integration, provider usability, and referral optimization, generating evidence to inform scalable imaging-supported triage models.
BEAT
Health Systems ProgramBuilding Echocardiography Access and Triage
A health systems implementation program designed to expand access to echocardiography in resource-constrained settings.
Focus: Through task-shifted service delivery, targeted training, and structured referral pathways, BEAT evaluates scalable approaches to improve diagnostic access, timely triage, and continuity of cardiovascular care.
A Cohesive Implementation Science Agenda
Together, these studies form an integrated research continuum linking diagnostic validation, digital triage, imaging access, and referral systems.
Implementation Outcomes
- Feasibility
- Adoption
- Fidelity
- Reach
- Sustainability
Research Continuum
- Diagnostic Validation
- Digital Triage
- Imaging Access
- Referral Systems
By embedding IRB-approved research into routine care environments, G-ACT produces generalizable evidence that supports responsible scale and lasting impact advancing equitable cardiovascular care where it is needed most.
Partner in Research
Join us in generating rigorous, actionable evidence to advance equitable cardiovascular care globally.