Rigorous Research
Real-World Impact
G-ACT's work is grounded in rigorous scientific evidence generated through independently governed, ethically approved research embedded within real-world health systems.
We prioritize interventions with established clinical validity and apply implementation science methods to determine how proven diagnostics, therapies, and care pathways can be adopted, integrated, and sustained in routine clinical practice particularly in resource-constrained settings.
DAMSUN-HF Study
AI-Enabled Digital Auscultation for Detecting Heart Failure
An IRB-approved, prospective validation and implementation study evaluating AI-enabled digital auscultation for detecting heart failure with reduced ejection fraction in frontline care.
The study's findings have been independently reported and published in Circulation, providing peer-reviewed evidence that high-performing cardiovascular diagnostic innovations can be deployed effectively within routine workflows when implementation is designed for context and system constraints.
Published & Recognized
The impact of DAMSUN-HF has been recognized across leading cardiovascular literature, reinforcing the relevance of our evidence beyond a single setting.
Circulation
American Heart Association
Peer-reviewed publication of DAMSUN-HF Study findings
JACC
Journal of the American College of Cardiology
Perspective/commentary recognizing DAMSUN-HF impact
Heart Failure Reviews
Independent Evaluation
Independent evaluation reinforcing evidence relevance
Importantly, this recognition underscores the need for implementation-focused pathways to scale, demonstrating that rigorous evidence generation within real-world contexts is essential for advancing equitable cardiovascular care.
Advancing Research Pipeline
Building on this foundation, G-ACT is advancing a pipeline of IRB-approved research programs designed to extend evidence generation across additional populations, care settings, and implementation contexts.
I-HEART
ActiveExtending evidence generation across additional populations, care settings, and implementation contexts.
INSIGHT
ActiveStructured to assess diagnostic performance, workflow integration, referral effectiveness, adoption, fidelity, and sustainability.
These studies are structured to assess not only diagnostic or clinical performance, but also real-world implementation outcomes such as workflow integration, referral effectiveness, adoption, fidelity, and sustainability—ensuring the evidence we generate is credible, generalizable, and directly actionable for health systems, policymakers, and funders.
Partner in Research
Join us in generating rigorous, actionable evidence to advance equitable cardiovascular care globally.